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Research Domain - Reproductive Health

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Avon Longitudinal Study of Parents and Children (ALSPAC), Growing and Changing (8), Mother/Daughter Questionnaire - 97 - 157 Months
#100103

Avon Longitudinal Study of Parents and Children (ALSPAC), Growing and Changing, Parent/Son Questionnaire- 97 - 157 Months
#100104

Avon Longitudinal Study of Parents and Children (ALSPAC), Growing and Changing (8), Female Teenage Questionnaire - 175 - 204 Months
#100101

Avon Longitudinal Study of Parents and Children (ALSPAC), Growing and Changing (8), Male Teenage Questionnaire
#100102

National Survey of Family Growth (NFSG), 2013-2015
#100204

National Survey of Family Growth (NFSG), Male, 2013-2015
#100203

National Survey of Family Growth (NFSG), 2013-2015
#100303

National Survey of Family Growth (NFSG), Male, 2013-2015
#100304

Slama, R., et al, Feasibility of the Current-Duration Approach to Studying Human Fecundity, EPIDEMIOLOGY, 2006
#100402

Pregnancy Study Online (PRESTO), Female Screener and Baseline Questionnaire
#100403

Slama, R., et al, Epidemiologic tools to study the influence of environmental factors on fecundity and pregnancy-related outcomes, EPIDEMIOL REVs, 2014
#100404

Black Womens Health Study (BWHS), 1995
#100601

Study for Future Families (SFF) & National Longitudinal Survey of Youth (NLSY)
#100602

Nurses Health Study II (NHS II), 2015
#100702

Behavioral Risk Factor Surveillance System (BRFSS), 2014
#100802

WHO Laboratory Manual for the Examination and Processing of Human Semen, Fifth Edition, 2010
#101601

Study For Future Families
#100901

Study for Future Families & International Index of Erectile Function (IIEF)
#101001

Nurses Health Study (NHS), Black Womens Health Study (BWHS), Study of Women Across the Nation (SWAN)
#101101

International Prostate Symptom Score (I-PSS)
#101202

National Survey of Family Growth (NSFG), 2011-2013
#100502

Womens Interview Study of Health & Pregnancy Risk Assessment Monitoring System (PRAMS), 2009
#101301

The Longitudinal Investigation of Fertility & the Environment (LIFE) Study, 2005
#101302

National Health and Nutrition Examination Survey (NHANES), Sexual Behavior Module, 2015-2016
#101704

National Health and Nutrition Examination Survey (NHANES), Sexual Behavior Module, 2015-2016
#101703

Melmed, S., et al. Williams textbook of endocrinology, 2008
#101501
Release Date:

February 26, 2010; reviewed April 11, 2017

Scope of Domain:
Scope Elements Final Protocols To Toolkit (26)
Maturation Assessment of Pubertal Development
Infertility, known infertility, cause of known infertility, any use of infertility treatment Causes and Treatments of Known Infertility
Contraceptive use (including hormonal contraception), voluntary sterilization, condom or other male-oriented contraceptive use Contraceptive Methods
Infertile periods (periods of unprotected sex without pregnancy) Difficulty in Conceiving
Surgical procedures (e.g., oophorectomy, hysterectomy) Female Reproductive Organ Surgical Procedures
Hormone replacement therapy Hormonal Therapy
HPV vaccinations, e.g., Gardasil Human Papillomavirus Use
Age at menarche; age at puberty; maturation, first-time masturbation/ejaculation, prepubertal questions History of Prepubertal Development
Hypogonadal, hypospadias, cryptorchidism, prepuberty Male Reproductive Tract Birth Defects
Age at menopause; extended periods of amenorrhea Menstrual History
Prostate diseases and symptoms Prostate Health
Number of pregnancies and spacing; outcome of each pregnancy; maternal complications (pregnancy-related death or morbidity); infant health parameters (preterm, low birth weight, congenital anomalies, gestational age); alcohol use; number of pregnancies fathered Reproductive History
Sexual difficulties Sexual Function, Male
Age at first intercourse; number of sexual partners Sexual History
Maturation through clinical exam Testes Development
Current sexual activity Current Sexual Activity (supplemental)
Rape and other sexual abuse Forced Sexual Activity (supplemental)
Working Group Roster:

WG Members:

Carol Hogue, PhD, Chair
Emory University
Atlanta, GA 		Stephanie Seminara, MD
Massachusetts General Hospital
Boston, MA
Andrea Dunaif, MD
Northwestern University
Evanston, IL 		Rebecca Sokol, MD
University of Southern California
Los Angeles, CA
Russ Hauser, MD, ScD
Harvard University
Belmont, MA 		Jun (Jim) Zhang, MD, PhD
Eunice Kennedy Shriver National Institute of Child Health and
Human Development (NICHD)
Rockville, MD
Pauline Mendola, PhD
Centers for Disease Control and Prevention
Prevention/National Center for Health Statistics
Hyattsville, MD

SC Liaison, WG Manager and WG Supervisor:

Michelle A. Williams, ScD, SC Liaison
Harvard School of Public Health
Boston, MA 		Sonja Hoover, MPP, WG Manager
RTI International
Waltham, MA
Richard Kwok, PhD, WG Supervisor
RTI International
Research Triangle Park, NC
Expert Review Panel 5 - Reproductive Health domain:

ERP Members:

John Amory, MD
University of Washington
Seattle, WA 		Courtney Lynch, PhD
The Ohio State University
Columbus, OH

SC Liaison, ERP Manager and ERP Supervisor:

Elaine M. Faustman, PhD, SC Liaison
University of Washington
Seattle, WA 		Lisa Cox, MS, ERP Manager
RTI International
Atlanta, GA
Michael Phillips, MS, ERP Supervisor
RTI International
Research Triangle Park, NC
Reproductive Health Supplemental Information includes:
Additional Information for Reproductive Health Measures:

There is no additional information for this domain.

Protocol Name ID Status DCW DD DD Mapping
Causes and Treatments of Known Infertility - Female 100202 updated N/A N/A N/A
Causes and Treatments of Known Infertility - Male 100201 updated N/A N/A N/A
Contraceptive Methods - Female 100301 replaced N/A N/A N/A
Contraceptive Methods - Male 100302 updated N/A N/A N/A
Difficulty in Conceiving 100401 replaced N/A N/A N/A
Female Reproductive Organ Surgical Procedures 100501 replaced N/A N/A N/A
History of Prepubertal Development - Female 100601 minor edits N/A N/A N/A
History of Prepubertal Development - Male 100602 minor edits N/A N/A N/A
Hormonal Therapy 100701 updated N/A N/A N/A
Human Papillomavirus Vaccine Use 100801 updated N/A N/A N/A
Male Reproductive Tract Birth Defects 100901 minor edits N/A N/A N/A
Male Sexual Function 101001 minor edits N/A N/A N/A
Menstrual History 101101 minor edits N/A N/A N/A
Prostate Health 101201 replaced N/A N/A N/A
Sexual History 101401 retired N/A N/A N/A
Sexual Risk Behavior - Female 101702 updated N/A N/A N/A
Sexual Risk Behavior - Male 101701 updated N/A N/A N/A
Testes Volume 101501 minor edits N/A N/A N/A
SI-Current_Sexual_Activity 000000 retired N/A N/A N/A
SI–Sexual Violence 000000 replaced N/A N/A N/A